Case series - Wikipedia

 

case series study definition

Jan 03,  · Case series are a commonly reported study design, but the label "case series" is used inconsistently and sometimes incorrectly. Mislabeling impairs the appropriate indexing and sorting of evidence. This article tries to clarify the concept of case series and proposes a way to distinguish them from cohort geeoffs.gq by: Definition of Case series in the geeoffs.gq dictionary. Meaning of Case series. What does Case series mean? Information and translations of Case series in the most comprehensive dictionary definitions resource on the web. A case series (also known as a clinical series) is a type of medical research study that tracks subjects with a known exposure, such as patients who have received a similar treatment, or examines their medical records for exposure and geeoffs.gqis of clinical trials: Risk–benefit ratio, .


What does Case series mean?


A total number of articles were retrieved. The number of patients and category of these articles were analyzed. Out of the articles categorized as case reports We suggest that a case series should have more than four patients while four paitents or less should be reported individually as case reports.

There has been a recent trend in some journals to stop publishing case reports and publish more original articles instead. This approach may have case series study definition negative impact on understanding the pathophysiology and management of rare diseases. Furthermore, group outcomes may not reflect exactly what happens in individual patients.

Historically, reporting case case series study definition with small number of patients raised important concerns regarding serious conditions like the relationship between liver adenomas and contraceptive pills, Kaposi's sarcoma and AIDS, and the toxic effects of high concentrations of oxygen on the optic nerve in newborn infants.

Some journals have gone around that by accepting case series instead of case reports or alternatively establish a sister journal for case reports so as not to lose this important advantage. Both case series study definition seperate types case series study definition observational studies. Some authors accepted even three cases to be a case series. We were personally lost between the instruction of authors and the personal opinion of editors on defining a case series.

Case series were some times rejected on the basis that they were considered by editors as case reports personal expereince. Search was limited to the title filed and the publication date between 1st of January to 31st of December The site was accessed on 18th of October Publications type was accessed on individual abstracts and tabbed. Some articles had more than one type which was vertically organized. The first line was considered as the first type, the second line as the second type, and the third line as the third type.

A total number of articles were displayed. The abstracts of these articles were printed and reviewed manually. The number of cases in each paper was searched manually on the hard copy. A total number of papers were included in the analysis, case series study definition. This was available only on out of articles One paper had a single case reported as case series in a prestigious journal.

Only one study 0. Other categories are shown in case series study definition 1. This covered a wide range of research designs including randomized controlled trials in three articles and meta-analysis in one article, case series study definition.

Publication type, as defined by the U. Number of subjects studied in papers published during by the U. Number of subjects of papers published during by the U.

An accurate observation may turn out to be the first step towards an important discovery in science. Similarly, many diseases were first observed at the bedside. A good descriptive study has a clear, specific, and measurrable definition of the studied disease. Furthermore, the design of observational studies and randomized trials answer different questions, case series study definition.

Both case reports and case series lack comparison groups, their data may be biased and incomplete, case series study definition. Despite that, case series study definition, they are useful for generating hypotheses for future studies. Other definitions indicate that a case series has few patients.

It is very clear from these definitions that there is no clear distinction between a case report and a case series in the literature. The results of our paper reflect this finding. Some papers, even in prestigious journals, case series study definition, considered one case as a case series 11 and another labeled a group of more than cases as a case series This misconception was also carried out to the definition of a case report.

The variance of the data, the difference between the means, and the power of a study will decide the sample size needed for a study. Finding a difference between two groups depends on the standard error of the mean of each of these groups. It is obvious that if data of a group of subjects are to be summarized statistically, then a minimum number of subjects is needed to be valid. We have found from experience that, five is the minimum reasonable number of independent subjects in a group so as to combine their data 23 — 25 That is because, the standard error of the mean, which is used for comparisons, will be much larger for a number of subjects less than that.

The standard error of the mean equals the standard deviation a marker of variation in the data divided by the square root of the sample size. Nevertheless, it is important to stress that the number of patients per se will not indicate the required research design. Case series will contain individual patients' data like demography, diagnosis, and management. Data of a small case series can be presented as a table and pooled together if needed without the need for individual detailed desription This may occasionally alert clinicians to unnoticed serious clincial events.

Furhtermore, a case series may have been collected over a specific period of time which should be mentioned in the paper. Case series study definition case series can be consecutive if all eligible patients were identified by the researchers during the study period. Alternatively, it case series study definition be nonconsecutive if it includes some, but not all, of the eligible patients.

We think that the distinction between a case report and a case series should be clear in the instruction of authors of different journals. This will save the time of the authors and editors and enhance the review process of medical journals. Some journals will accept only a case series design but not a case report. We suggest that patients less than 5 to be reported individually as case reports and those above 4 to be presented as a case series.

The upper limit of a case series could not be defined by us but we suggest ten as an upper limit, similar to what was suggested by the European Urology An observational study of more patients based on rates is a different category and should be possibly labeled as a rate-based descriptive study, case series study definition. We tried to analyze this concept and came with a suggestion that a case series should have more than four patients while four paitents or less should be reported individually as case reports, case series study definition.

We hope that our suggestion will be accepted by the scientific community. National Center for Biotechnology InformationU. Journal List Afr Health Sci v. Afr Health Sci. Author information Copyright and License information Disclaimer. This article has been cited by other articles in PMC. Keywords: Case report, case series, concept analysis, research design.

Introduction Case series study definition has been a recent trend in some journals to stop publishing case reports and publish more original articles instead. Table 1 Publication type, as defined by the U. Publication type First type Second type Third type Case reports Open in a separate window. Figure 1. Figure 2. Discussion An accurate observation may turn out to be the first step towards an important discovery in science. Statistical and study design considerations The variance of the data, the difference between the means, and the power of a study will decide the sample size needed for a study.

References 1. International Journal of Surgery. World Journal of Surgery. Mant D. Can randomised trials inform clinical decisions about individual patients?

Pollock AV. Surgical evaluation at the crossroads. Br J Surg. Descriptive studies: what they can and cannot do. Cases Journal. Case reports and case series in prehospital emergency care research, case series study definition. Emerg Med J. Epidemiology in Medicine. First edition. PubMed website. Hassard TH. In: Hassard TH, editor. Understanding biostatistics. Louis: Mosby year book, Inc. Chylous ascites requiring surgical intervention after donor nephrectomy: case series and single center experience.

Am J Transplant. Novel optometrist-led all Wales primary eye-care services: evaluation of a prospective case series. Br J Ophthalmol. How to design a good case series.

 

Case series | definition of case series by Medical dictionary

 

case series study definition

 

Aug 22,  · A retrospective case-control uses these two groups and looks back to the past for data and possible risk factors. A matched case-control study chooses controls based on some matching factor, like age, weight or severity of disease. Retrospective Case Series. A case-series is . In the social sciences and life sciences, a case study is a research method involving an up-close, in-depth, and detailed examination of a subject of study (the case), as well as its related contextual conditions.. Case studies can be produced by following a formal research method. These case studies are likely to appear in formal research venues, as journals and professional conferences. Jul 17,  · Consequently, a case series cannot be comparative. The definition of a case series by Dekkers et al. is summarized in Table 4. It is noteworthy that the conceptualization also ensures a clear distinction of case series from other study designs that apply outcome-based geeoffs.gq by: